The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen Information
Immunogen
Fusion protein of human ELF5
Swissprot
Q9UKW6
Synonyms
E74 like factor 5 (ets domain transcription factor)E74 like factor 5E74-like factor 5ELF 5ELF5ELF5Epithelium restricted ESE 1 related Ets factorEpithelium restricted ESE1 related Ets factorEpithelium specific Ets transcription factor 2Epithelium-