ENSA Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD88277A
Western blot analysis of extracts of various cell lines using ENSA Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using ENSA Polyclonal Antibody at 1:1000 dilution.
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Overview

Circle
Product Name
ENSA Polyclonal Antibody
Catalog Number
RD88277A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.

Immunogen Information

Circle
Immunogen
A synthetic peptide of human ENSA
Gene ID
2029
Swissprot
O43768
Synonyms
ENSAARPP-19e
Calculated MW
25kDa/30kDa/40kDa/50kDa/55kDa
Observed MW
50KDa

Applications

Circle
Reactivity
Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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