EPCAM Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78484A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using EPCAM Polyclonal Antibody at dilution 1:45
Product Name
EPCAM Polyclonal Antibody
Catalog Number
RD78484A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. EpCAM is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signalling and polarity. It has been used as an immunotherapeutic target in the treatment of gastrointestinal, urological and other carcinomas. It is expressed in undifferentiated pluripotent stem cells.tufting enteropathy.
Immunogen Information
Immunogen
Synthetic peptide of human EPCAM
Swissprot
P16422
Synonyms
17 1A323/A3Adenocarcinoma associated antigenAdenocarcinoma-associated antigenAntigen identified by monoclonal AUA1AUA1CD326CD326 antigenCell surface glycoprotein Trop 1Cell surface glycoprotein Trop 2Cell surface glycoprotein Trop-1CO 17ACO17
Gene Accession
NP_002345
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas