Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.
Immunogen Information
Immunogen
Synthetic peptide of human EPHB3
Swissprot
P54753
Synonyms
Cek10EK2Embryonic kinase 2EPH Like Tyrosine Kinase 2EPH receptor B3EPH-like kinase 2ephb3EPHB3Ephrin receptor EphB3Ephrin type B receptor 3Ephrin type-B receptor 3ETK2hEK2Human Embryo Kinase 2Mdk5Sek4TYRO6Tyrosine protein kinase receptor
Gene Accession
NP_004434
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4