This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human EPHB6
Swissprot
O15197
Synonyms
EPH receptor B6Ephb6EPHB6Ephrin type B receptor 6 precursorEphrin type-B receptor 6HEPMGC129910MGC129911Tyrosine protein kinase defective receptor EPH 6Tyrosine-protein kinase-defective receptor EPH-6
Gene Accession
BC110606
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4