EPS15 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD217923A
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using EPS15 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using EPS15 Polyclonal Antibody at dilution of 1:50(×200)
Product Name
EPS15 Polyclonal Antibody
Catalog Number
RD217923A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15) is a Protein Coding gene. Diseases associated with EPS15 include Vaccinia. Among its related pathways are Notch signaling pathway (KEGG) and HIV Life Cycle. GO annotations related to this gene include calcium ion binding and SH3 domain binding. An important paralog of this gene is EPS15L1.
Immunogen Information
Immunogen
Synthetic peptide of human EPS15
Swissprot
P42566
Synonyms
AF 1PAF 1p proteinAF1PALL1 fused gene from chromosome 1Epidermal growth factor receptor pathway substrate 15Epidermal growth factor receptor substrate 15EPS 15MLLT 5MLLT5Protein Eps 15Protein Eps15
Gene Accession
NP001972
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas