EPS15L1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD84742A
Western blot analysis of extracts of various cell lines using EPS15L1 Polyclonal Antibody at dilution of 1:1000.
Product Name
EPS15L1 Polyclonal Antibody
Catalog Number
RD84742A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.
Immunogen Information
Immunogen
Recombinant fusion protein of human EPS15L1 (NP_001245304.1).
Gene ID
58513
Swissprot
Q9UBC2
Synonyms
EPS15L1EPS15R
Calculated MW
66 kDa/83 kDa/94 kDa/99 kDa
Observed MW
110 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas