EPS15L1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75525A
Western Blot analysis of Hela, PC3, 231 and 293T cell using EPS15L1 Polyclonal Antibody at dilution of 1:350
Immunohistochemistry of paraffin-embedded Human thyroid cancer using EPS15L1 Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human colon cancer using EPS15L1 Polyclonal Antibody at dilution of 1:30
Product Name
EPS15L1 Polyclonal Antibody
Catalog Number
RD75525A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.
Immunogen Information
Immunogen
Recombinant protein of human EPS15L1
Swissprot
Q9UBC2
Synonyms
EP15Repidermal growth factor receptor pathway substrate 15- ike 1Epidermal growth factor receptor substrate 15 like 1Epidermal growth factor receptor substrate 15-like 1epidermal growth factor receptor substrate EPS15REps15 related proteinEps15-rela
Calculated MW
94 kDa
Gene Accession
BC131590
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas