The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Fusion protein of human ERAL1
Swissprot
O75616
Synonyms
CEGAConserved ERA like GTPaseConserved ERA-like GTPaseERAEra (E.coli G protein homolog) like 1Era G protein like 1 (E.coli)Era G protein like 1ERA WERA-like protein 1ERA-WEral1ERAL1ERAL1AERAWGTP binding protein era homologGTPase EraGTPase