ERCC1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219768A
Western blot analysis of 293T and NIH/3T3 cell Mouse liver tissue lysates using ERCC1 Polyclonal Antibody at dilution of 1:600
Product Name
ERCC1 Polyclonal Antibody
Catalog Number
RD219768A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5'-incision during DNA repair. It forms a complex with ERCC11,XPF and ERCC4,which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1,together with RRM1,are determinants of survival after surgical treatment of early-stage,non-small-cell lung cancer. (Ref: Simon,ER. 2005)
Immunogen Information
Immunogen
Synthetic peptide of human ERCC1
Swissprot
P07992
Synonyms
COFS 4COFS4DNA excision repair protein ERCC 1DNA excision repair protein ERCC-1DNA excision repair protein ERCC1ERCC 1ERCC1ERCC1Excision repair cross complementation group 1Excision repair cross complementing 1Excision Repair Cross Complementing
Calculated MW
33 kDa
Observed MW
Refer to figures
Gene Accession
NP001974
Applications
Reactivity
Human, Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
1.1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas