Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).
Immunogen Information
Immunogen
Recombinant Protein of ERK1 of MAPK3
Swissprot
P27361
Synonyms
ERK 1ERKERK-1ERK1ERT 2ERT2Extracellular Signal Regulated Kinase 1Extracellular signal related kinase 1Extracellular signal-regulated kinase 1HGNC6877HS44KDAPHUMKER1AInsulin Stimulated MAP2 KinaseInsulin-stimulated MAP2 kinaseMAP kinase 1MAP
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC-p
Conjugation
Unconjugated
Dilution
IHC 1:100-200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4