ERP44 is a 406 amino acid protein that contains one thioredoxin domain, a motif that participates in various redox reactions throughout the cell. Localized to the lumen of the endoplasmic reticulum (ER), TXNDC4 functions to inhibit the activity of IP3R-I (inositol 1,4,5-triphosphate receptor,type 1) within calcium channels. In addition, TXNDC4 is thought to regulate oxidative protein folding within the ER and may be involved in retaining proteins.
Immunogen Information
Immunogen
Synthetic peptide of human ERP44
Swissprot
Q9BS26
Synonyms
Endoplasmic reticulum resident protein 44Endoplasmic reticulum resident protein 44 kDaEndoplasmic reticulum resident protein ERp44ER protein 44ERp44ERP44KIAA0573PDIA10Protein disulfide isomerase family Amember 10Thioredoxin domain containing 4 (
Calculated MW
47 kDa
Gene Accession
NP_055866
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-2000, IHC 1:25-100, ELISA 1:2000-5000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4