ERVW-1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77181A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ERVW-1 Polyclonal Antibody at dilution 1:45
Product Name
ERVW-1 Polyclonal Antibody
Catalog Number
RD77181A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta.
Immunogen Information
Immunogen
Synthetic peptide of human ERVW-1
Swissprot
Q9UQF0
Synonyms
Endogenous retrovirus group W member 1ENVEnvelope polyprotein gPr73EnverinENVWERVWE1HERV-7qHERV-7q Envelope proteinHERV-W envelope proteinHERV-W-ENVHERV-W_7q21.2 provirus ancestral Env polyproteinHERV7QHERVWHERVWENVSyncytin 1SyncytinSyncyt
Gene Accession
NP_055405
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
1.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas