This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways.
Immunogen Information
Immunogen
Recombinant protein of human ESRRG
Swissprot
P62508
Synonyms
DKFZp781L1617ERR 3ERR G2ERR gamma 2ERR gamma-2ERR3ERR3ERRG 2ERRG2ERRgammaESRRGEstrogen receptor related protein 3Estrogen receptor-related protein 3Estrogen-related receptor gammaFLJ16023KIAA0832NR3B3Nuclear receptor subfamily 3 group B m
Calculated MW
51 kDa
Gene Accession
BC064700
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4