EXD2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218841A
Western blot analysis of Mouse brain tissue and Human cerebrum tissue lysates using EXD2 Polyclonal Antibody at dilution of 1:700
Immunohistochemistry of paraffin-embedded Human tonsil tissue using EXD2 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using EXD2 Polyclonal Antibody at dilution of 1:55(×200)
Product Name
EXD2 Polyclonal Antibody
Catalog Number
RD218841A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
Immunogen Information
Immunogen
Fusion protein of human EXD2
Swissprot
Q9NVH0
Synonyms
4930539P14RikC14orf114C85658DKFZp781A0133DKFZp781L15100Exd2EXD2EXDL2Exonuclease 3''-5'' domain-containing protein 2Exonuclease 3''-5'' domain-like-containing protein 2exonuclease 3'-5' domain-like 2FLJ10738RGD1311087
Calculated MW
70 kDa
Observed MW
Refer to figures
Gene Accession
BC001962
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas