The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Immunogen Information
Immunogen
Recombinant protein of human EZR
Swissprot
P15311
Synonyms
Villin 2 ezrinCVILCVLCytovillin 2CytovillinDKFZp762H157Epididymis secretory protein Li 105EZREZRIEzrinFLJ26216HEL S 105MGC1584p81VIL 2VIL2Villin 2 (ezrin)Villin 2Villin-2Villin2
Calculated MW
69 kDa
Gene Accession
BC013903
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4