Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Immunogen Information
Immunogen
Synthesized peptide derived from the C-terminal region of human Ezrin
Swissprot
P15311
Synonyms
Villin 2 ezrinCVILCVLCytovillin 2CytovillinDKFZp762H157Epididymis secretory protein Li 105EZREZRIEzrinFLJ26216HEL S 105MGC1584p81VIL 2VIL2Villin 2 (ezrin)Villin 2Villin-2Villin2
Calculated MW
69 kDa
Observed MW
70 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4