Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
Immunogen Information
Immunogen
Synthetic peptide of human FAAP24
Swissprot
Q9BTP7
Synonyms
C19ORF40C19orf40 chromosome 19 open reading frame 40FAAP24Fanconi anemia-associated protein 24 kDaFanconi anemia-associated protein of 24 kDaFAP24MGC32020