The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group F.
Immunogen Information
Immunogen
Recombinant protein of human FANCF
Swissprot
Q9NPI8
Synonyms
A730016A17FACFFAFFANCFFANCFFanconi anemia complementation group FFanconi anemia group F proteinMGC126856Protein FACFRGD1561456
Gene Accession
NP_073562
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4