Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
Immunogen Information
Immunogen
Synthetic peptide of human FBLN1
Swissprot
P23142
Synonyms
Basement membrane protein 90BM 90FBLNFbln1FBLN1FIBL 1FIBL-1FIBL1Fibulin 1Fibulin-1
Gene Accession
NP_001987
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4