This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Synthetic peptide of human FBXL4
Swissprot
Q9UKA2
Synonyms
F box and leucine rich repeat protein 4F box protein FBL4/FBL5F box/LRR repeat protein 4F-box and leucine-rich repeat protein 4F-box protein FBL 4F-box protein FBL4/FBL5F-box/LRR-repeat protein 4FBL 4FBL 5FBL4FBL5Fbxl4FBXL4MTDPS13
Gene Accession
NP036292
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.66 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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