This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats.
Immunogen Information
Immunogen
Recombinant protein of human FBXW7
Swissprot
Q969H0
Synonyms
AGOArchipelagoArchipelago homologArchipelagoDrosophilahomolog ofCDC4CDC4S.cerevisiaehomolog ofDKFZp686F23254F box and WD 40 domain protein 7 (archipelago homologDrosophila)F box and WD 40 domain protein 7F box and WD repeat domain containing
Gene Accession
BC117244
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4