FCGR3A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78177A
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using FCGR3A Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human brain tissue using FCGR3A Polyclonal Antibody at dilution 1:60
Product Name
FCGR3A Polyclonal Antibody
Catalog Number
RD78177A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.
Immunogen Information
Immunogen
Recombinant protein of human FCGR3A
Swissprot
P08637
Synonyms
CD 16CD 16aCD16CD16aCD16a antigenCD16BCD16b antigenFc fragment of IgGFc fragment of IgG low affinity IIIa receptor (CD16)Fc fragment of IgG low affinity IIIa receptorFc fragment of IgG receptor IIIaFc fragment of IgGlow affinity IIIreceptor (
Gene Accession
BC033678
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas