This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Human CD16A
Swissprot
P08637
Synonyms
CD 16CD 16aCD16CD16aCD16a antigenCD16BCD16b antigenFc fragment of IgGFc fragment of IgG low affinity IIIa receptor (CD16)Fc fragment of IgG low affinity IIIa receptorFc fragment of IgG receptor IIIaFc fragment of IgGlow affinity IIIreceptor (
Calculated MW
29 kDa
Observed MW
55 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
420 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4