The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.
Immunogen Information
Immunogen
Synthetic peptide of human FGF10
Swissprot
O15520
Synonyms
BB213776fd11d03FGF 10FGF-10FGF10FGF10_HUMANFibroblast growth factor 10Keratinocyte growth factor 2KGF 2Produced by fibroblasts of urinary bladder lamina propriawu:fd11d03zgc:109774