FHIT Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75831A
Western Blot analysis of Mouse kidney and Human kidney tissue using FHIT Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human colon cancer using FHIT Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human cervical cancer using FHIT Polyclonal Antibody at dilution of 1:30
Product Name
FHIT Polyclonal Antibody
Catalog Number
RD75831A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human FHIT
Swissprot
P49789
Synonyms
AP3A hydrolaseAP3A hydrolase fragile site 3p14.2AP3AaseBis 5' adenosyl triphosphataseBis(5' adenosyl) triphosphataseDiadenosine 5' 5''' P1 P3 triphosphate hydrolaseDinucleosidetriphosphataseFRA 3BFRA3BFragile histidine triadFragile histidine tri
Calculated MW
17 kDa
Gene Accession
BC032336
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas