FITC Anti-Human CD86 Antibody[IT2.2]
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30659F
Human peripheral blood are stained with APC Anti-Human CD14 Antibody and FITC Anti-Human CD86 Antibody (Left). Cells in the monocyte gate were used for analysis. Cells are stained with APC Anti-Human CD14 Antibody and FITC Mouse IgG2b, κ Isotype Control (Right).
Product Name
FITC Anti-Human CD86 Antibody[IT2.2]
Catalog Number
RD30659F
Isotype
Mouse IgG2b, κ
Host
Mouse
Background
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Immunogen Information
Gene ID
942
Synonyms
T-lymphocyte activation antigen CD86CD28LG2B7-2B70
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
FITC
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.