FITC Anti-Human CD8a Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Human pheripheral blood cells are stained  with Anti-Human CD8 Monoclonal Antibody(FITC Conjugated)(filled gray histogram). Unstained pheripheral blood cells (blank black histogram) are used as control.
Human pheripheral blood cells are stained with Anti-Human CD8 Monoclonal Antibody(FITC Conjugated)(filled gray histogram). Unstained pheripheral blood cells (blank black histogram) are used as control.
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Overview

Circle
Product Name
FITC Anti-Human CD8a Antibody
Catalog Number
RD21337F
Clonality
Monoclonal
Isotype
Mouse IgG2a, κ
Host
Mouse

Background

Circle
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

Immunogen Information

Circle
Gene ID
925
Swissprot
P01732
Synonyms
T-cell surface glycoprotein CD8 alpha chainCD8AT-lymphocyte differentiation antigen T8/Leu-2MAL

Applications

Circle
Reactivity
Human
Tested Applications
FCM
Conjugation
FITC
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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