FITC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30646F
C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Anti-Mouse CD366/Tim-3 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Rat IgG2a, κ Isotype Control (Right).
Product Name
FITC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]
Catalog Number
RD30646F
Isotype
Rat IgG2a, κ
Host
Rat
Background
CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
Immunogen Information
Gene ID
84868
Synonyms
TIM3TIMD3HAVcr-2TIMD-3
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
FITC
Concentration
0.5 mg/mL
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.