FITC Anti-Mouse CD62L Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD20231F
C57BL/6 murine splenocytes are stained with Anti-Mouse CD62L Monoclonal Antibody(FITC Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
Product Name
FITC Anti-Mouse CD62L Antibody
Catalog Number
RD20231F
Clonality
Monoclonal
Isotype
Rat IgG2a, κ
Host
Rat
Background
CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.
Immunogen Information
Gene ID
20343
Swissprot
P18337
Synonyms
L-selectinSellCD62 antigen-like family member LLAM-1LECAM1Lymph node homing receptorLy-22CD62LLnhrLy22
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
FITC
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Research Areas