FITC Anti-Mouse Ly6A/E(Sca-1) Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD22094F
C57BL/6 murine splenocytes are stained with Anti-Mouse Ly6A/E(Sca-1) Monoclonal Antibody(FITC Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
Variation
Quantity
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Overview
Product Name
FITC Anti-Mouse Ly6A/E(Sca-1) Antibody
Catalog Number
RD22094F
Clonality
Monoclonal
Isotype
Rat IgG2a, κ
Host
Rat
Background
Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
Immunogen Information
Gene ID
110454
Swissprot
P05533
Synonyms
Ly6aLy6Ly-6A.2/Ly-6E.1SCA-1TAP
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
FITC
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.