FKBP1A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FKBP1A Polyclonal Antibody at dilution of 1:55(×200)
Product Name
FKBP1A Polyclonal Antibody
Catalog Number
RD252794A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.
Immunogen Information
Immunogen
Fusion protein of human FKBP1A
Swissprot
P62942
Synonyms
12 kDa FK506-binding protein12 kDa FKBPCalstabin 1FK506 binding protein 1FK506 binding protein 12FK506 binding protein 1A (12kD)FK506 binding protein 1A 12kDaFK506 binding protein 1AFK506 binding protein T cell 12 kDFK506 binding proteinT cell1
Gene Accession
BC005147
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas