FKBP4 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD252964A
Western blot analysis of 293T 231 K562 Jurkat and Hela cell lysates  using FKBP4 Polyclonal Antibody at dilution of 1:700
Western blot analysis of 293T 231 K562 Jurkat and Hela cell lysates using FKBP4 Polyclonal Antibody at dilution of 1:700
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using FKBP4 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using FKBP4 Polyclonal Antibody at dilution of 1:50(×200)
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Overview

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Product Name
FKBP4 Polyclonal Antibody
Catalog Number
RD252964A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.

Immunogen Information

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Immunogen
Fusion protein of human FKBP4
Swissprot
Q02790
Synonyms
51 kDa FK506-binding protein52 kDa FK506 binding protein52 kDa FK506-binding protein52 kDa FKBP59 kDa immunophilinFK506 binding protein 4FK506-binding protein 4FKBP 4FKBP 52FKBP 59FKBP-4FKBP-52FKBP4FKBP4FKBP51FKBP52 proteinFKBP59HBIHsp 5
Calculated MW
52 kDa
Observed MW
Refer to figures
Gene Accession
BC001786

Applications

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Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
0.84 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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