FKBP5 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD217966A
Western blot analysis of A172 Hela HepG2 K562 and PC3 cell lysates  using FKBP5 Polyclonal Antibody at dilution of 1:600
Western blot analysis of A172 Hela HepG2 K562 and PC3 cell lysates using FKBP5 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using FKBP5 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using FKBP5 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using FKBP5 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FKBP5 Polyclonal Antibody at dilution of 1:50(×200)
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Overview

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Product Name
FKBP5 Polyclonal Antibody
Catalog Number
RD217966A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Immunogen Information

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Immunogen
Synthetic peptide of human FKBP5
Swissprot
Q13451
Synonyms
51 kDa FK506 binding protein 551 kDa FK506 binding protein51 kDa FK506-binding protein51 kDa FKBP54 kDa progesterone receptor associated immunophilin54 kDa progesterone receptor-associated immunophilinAIG 6AIG6Androgen regulated protein 6Androgen
Calculated MW
51 kDa
Observed MW
Refer to figures
Gene Accession
NP004108

Applications

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Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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