FLNA Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD84787A
Immunohistochemistry of paraffin-embedded Human colon muscle using FLNA Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human breast cancer using FLNA Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human uterine cancer using FLNA Polyclonal Antibody at dilution of 1:100 (40x lens).
Variation
Quantity
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Overview
Product Name
FLNA Polyclonal Antibody
Catalog Number
RD84787A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
A synthetic peptide of human FLNA (NP_001104026.1).
Gene ID
2316
Swissprot
P21333
Synonyms
FLNAABP-280ABPXCSBSCVD1FLNFLN-AFLN1FMDMNSNHBPOPDOPD1OPD2XLVDXMVDfilamin-A
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas