FLNA Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75835A
Western Blot analysis of PC3, Hela, NIH/3T3 and HUVEC cell using FLNA Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human liver cancer using FLNA Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human brain using FLNA Polyclonal Antibody at dilution of 1:40
Product Name
FLNA Polyclonal Antibody
Catalog Number
RD75835A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human FLNA
Swissprot
P21333
Synonyms
ABP 280ABP-280Actin-binding protein 280Alpha filaminAlpha-filaminAPBXCSBSCVD1Endothelial actin binding proteinEndothelial actin-binding proteinFilamin 1Filamin A alphaFilamin AFilamin-1Filamin-AFLNFLN-AFLN1FLNAFLNAFMDMNSNHBPNon musc
Calculated MW
281 kDa
Gene Accession
NP_001104026
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas