FLNC Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD81186A
Western blot analysis of extracts of various cell lines using FLNC Polyclonal Antibody at dilution of 1:3000.
Western blot analysis of extracts of various cell lines using FLNC Polyclonal Antibody at dilution of 1:3000.
Immunofluorescence analysis of HeLa cells using FLNC Polyclonal Antibody at dilution of  1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of HeLa cells using FLNC Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Overview

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Product Name
FLNC Polyclonal Antibody
Catalog Number
RD81186A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

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Immunogen
Recombinant fusion protein of human FLNC (NP_001449.3).
Gene ID
2318
Swissprot
Q14315
Synonyms
FLNCABP-280ABP280AABPAABPLCMH26FLN2MFM5MPD4RCM5filamin-C
Calculated MW
287 kDa/291 kDa
Observed MW
302 kDa

Applications

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Reactivity
Human,Mouse
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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