FOLR1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219878A
Immunohistochemistry of paraffin-embedded Human tonsil tissue using FOLR1 Polyclonal Antibody at dilution of 1:80(×200)
Product Name
FOLR1 Polyclonal Antibody
Catalog Number
RD219878A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Folate receptor 1 (FOLR1),also known as folate receptor alpha or adult folate-binding protein (FBP),is a 38-kDa glycoprotein belonging to the folate receptor family . The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung,kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer,non-small cell lung cancer,breast cancer,kidney cancer and high-grade osteosarcoma .
Immunogen Information
Immunogen
Synthetic peptide of human FOLR1
Swissprot
P15328
Synonyms
adultAdult folate binding proteinAdult folate-binding proteinFBPFolate Receptor 1 AdultFolate receptor 1Folate Receptor 1 PrecursorFolate receptor adultFolate receptor alphaFolate receptorFOLRFOLR1FOLR1FR alphaFR-alphaFRalphaKB cells FBPM
Gene Accession
NP000793
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
2.28 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas