FOXL2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78502A
Western Blot analysis of Mouse brain and heart tissue using FOXL2 Polyclonal Antibody at dilution of 1:750
Variation
Quantity
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Overview
Product Name
FOXL2 Polyclonal Antibody
Catalog Number
RD78502A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Immunogen Information
Immunogen
Synthetic peptide of human FOXL2
Swissprot
P58012
Synonyms
BlepharophimosisBlepharophimosis epicanthus inversus and ptosis 1Blepharophimosis epicanthus inversus and ptosisBPES 1BPESBPES1Epicanthus inversus and ptosis 1Forkhead box L2Forkhead box protein L2Forkhead transcription factor FOXL2FOX L2FOXL 2
Calculated MW
50 kDa
Gene Accession
NP_075555
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas