Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence.
Immunogen Information
Immunogen
Synthesized peptide derived from human FoxO1 around the non-phosphorylation site of Ser319.
Swissprot
Q12778
Synonyms
FKH 1FKH1FKHRForkhead (Drosophila) homolog 1 (rhabdomyosarcoma)Forkhead box O1Forkhead box protein O1Forkhead box protein O1AForkhead in rhabdomyosarcomaForkheadDrosophilahomolog ofin rhabdomyosarcomaFoxO transcription factorfoxo1FOXO1FOXO1
Calculated MW
70 kDa
Observed MW
78 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4