This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human FOXO4
Swissprot
P98177
Synonyms
AFXAFX1AfxhALL1-fused gene from X chromosomeFork head domain transcription factor AFX1Forkhead box O4Forkhead box protein O4FOXO 4Foxo4FOXO4MGC117660MGC120490Mixed lineage leukemiatranslocated to7MLLT7Myeloid/lymphoid or mixed lineage leuk