This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Immunogen Information
Immunogen
Recombinant protein of human FTO
Swissprot
Q9C0B1
Synonyms
AlkB homolog 9ALKBH9Alpha-ketoglutarate-dependent dioxygenase FTOAW743446Fat mass and obesity-associated proteinFATSOMOUSEHOMOLOG OFFtoFTOGDFDKIAA1752mKIAA1752Protein fatso
Calculated MW
58 kDa
Gene Accession
BC003583
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4