FTO Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD75842A
Western Blot analysis of Human fetal brain tissue using FTO Polyclonal Antibody at dilution of 1:650
Western Blot analysis of Human fetal brain tissue using FTO Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human breast cancer using FTO Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human breast cancer using FTO Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human esophagus cancer using FTO Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human esophagus cancer using FTO Polyclonal Antibody at dilution of 1:60
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Overview

Circle
Product Name
FTO Polyclonal Antibody
Catalog Number
RD75842A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Immunogen Information

Circle
Immunogen
Recombinant protein of human FTO
Swissprot
Q9C0B1
Synonyms
AlkB homolog 9ALKBH9Alpha-ketoglutarate-dependent dioxygenase FTOAW743446Fat mass and obesity-associated proteinFATSOMOUSEHOMOLOG OFFtoFTOGDFDKIAA1752mKIAA1752Protein fatso
Calculated MW
58 kDa
Gene Accession
BC003583

Applications

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Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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