FUS Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD79500A
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using FUS Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using FUS Polyclonal Antibody at dilution 1:40
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Overview

Circle
Product Name
FUS Polyclonal Antibody
Catalog Number
RD79500A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Immunogen Information

Circle
Immunogen
Fusion protein of human FUS
Swissprot
P35637
Synonyms
75 kDa DNA pairing protein75 kDa DNA-pairing proteinALS6Amyotrophic lateral sclerosis 6fusFUS CHOPFus like proteinFUSFUS1Fused in sarcomaFusion (involved in t(12;16) in malignant liposarcoma)Fusion derived from t(12;16) malignant liposarcomaFu
Gene Accession
BC000402

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-150, ELISA 1:2000-10000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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