FZD8 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78803A
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using FZD8 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FZD8 Polyclonal Antibody at dilution 1:50
Product Name
FZD8 Polyclonal Antibody
Catalog Number
RD78803A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Immunogen Information
Immunogen
Synthetic peptide of human FZD8
Swissprot
Q9H461
Synonyms
Frizzled 8 seven transmembrane spanning receptorfrizzled 8seven transmembrane spanning receptorFrizzled family receptor 8frizzled homolog 8 (Drosophila)Frizzled homolog 8Frizzled-8FZ 8Fz-8FZ8FZD 8FZD8FZD8hFZ 8hFz8HGNC4046Homolog of Drosoph
Gene Accession
NP_114072
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas