GAD2 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD78507A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using GAD2  Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using GAD2 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human brain  tissue using GAD2  Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human brain tissue using GAD2 Polyclonal Antibody at dilution 1:30
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Overview

Circle
Product Name
GAD2 Polyclonal Antibody
Catalog Number
RD78507A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Immunogen Information

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Immunogen
Synthetic peptide of human GAD2
Swissprot
Q05329
Synonyms
65 kDa glutamic acid decarboxylaseDCE 2DCE2DCE2GAD 2GAD 65GAD-2GAD-65Gad2Glutamate decarboxylase 2 (pancreas)Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa)Glutamate decarboxylase 2Glutamate Decarboxylase 65Glutamate decarboxyla
Gene Accession
NP_000809

Applications

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Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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