GAD2 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD78507A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using GAD2  Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using GAD2 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human brain  tissue using GAD2  Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human brain tissue using GAD2 Polyclonal Antibody at dilution 1:30
Variation
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Overview
Circle
Product Name
GAD2 Polyclonal Antibody
Catalog Number
RD78507A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Immunogen Information
Circle
Immunogen
Synthetic peptide of human GAD2
Swissprot
Q05329
Synonyms
65 kDa glutamic acid decarboxylaseDCE 2DCE2DCE2GAD 2GAD 65GAD-2GAD-65Gad2Glutamate decarboxylase 2 (pancreas)Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa)Glutamate decarboxylase 2Glutamate Decarboxylase 65Glutamate decarboxyla
Gene Accession
NP_000809
Applications
Circle
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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