GADD45B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75846A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using GADD45B Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human brain tissue using GADD45B Polyclonal Antibody at dilution 1:30
Product Name
GADD45B Polyclonal Antibody
Catalog Number
RD75846A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
Immunogen Information
Immunogen
Recombinant protein of human GADD45B
Swissprot
O75293
Synonyms
GA45BGADD45 BetaGadd45bGADD45BETAGrowth arrest and DNA damage inducible 45 betaGrowth arrest and DNA damage inducible betaGrowth arrest and DNA damage-inducible gene GADD45betaGrowth arrest and DNA damage-inducible protein GADD45 betaGrowth arres
Gene Accession
BC113466
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.