Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis .
Immunogen Information
Immunogen
Recombinant protein corresponding to Mouse Mac2
Swissprot
P17931,P08699,P16110
Synonyms
35 kDa lectinCarbohydrate binding protein 35Carbohydrate-binding protein 35CBP 35CBP35Gal-3GAL3Galactose-specific lectin 3Galactoside-binding proteinGALBPGalectin 3 internal geneincludedGalectin-3Galectin3GALIGGBPIgE binding proteinIgE-bi
Calculated MW
30 kDa
Observed MW
30 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
370 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4