GALNT4 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD89614A
Western blot analysis of extracts of HeLa cells using GALNT4 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of HeLa cells using GALNT4 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of Rat brain using GALNT4 Polyclonal Antibody at 1:500 dilution.
Western blot analysis of extracts of Rat brain using GALNT4 Polyclonal Antibody at 1:500 dilution.
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Overview

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Product Name
GALNT4 Polyclonal Antibody
Catalog Number
RD89614A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist.

Immunogen Information

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Immunogen
Recombinant fusion protein of human GALNT4
Gene ID
8693
Swissprot
Q8N4A0
Synonyms
GALNT4GALNAC-T4GALNACT4
Calculated MW
66kDa/72kDa/79kDa/82kDa/84kDa/86kDa
Observed MW
120kDa

Applications

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Reactivity
Human,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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