The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
Immunogen Information
Immunogen
Synthetic peptide of human GALR1
Swissprot
P47211
Synonyms
gal receptor 1gal-1 receptorGAL1Rgalanin receptor 1galanin receptor 1brainGalanin receptorGalanin receptor type 1galanin-1 receptorGALNRGALNR1GALR1hugal 1-r